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On Friday afternoon, dozens of first responders were on the scene as a significant blaze engulfed the top story of the Graystone Inn. Officials reported no injuries, but the cause of the fire was not immediately known.

Drug deaths are declining but the Trump administration's intelligence team has issued a new report describing street fentanyl as a top threat to the U.S.

Khamenei, the Islamic Republic's second supreme leader, has been killed. He had held power since 1989, guiding Iran through difficult times — and overseeing the violent suppression of dissent.

On the first Sunday of the Olympic Winter Games, downhill skier Breezy Johnson captured the first gold for Team USA. And Alpine racer Lindsey Vonn crashed and was transported to the hospital with a broken leg.

The FDA's controversial vaccine chief, Dr. Vinay Prasad, is leaving the agency. It's the second time he has abruptly departed following decisions involving the review of vaccinations and specialty drugs.

Experts who spent months negotiating a 2015 nuclear agreement with Iran say mutual mistrust, starkly different negotiating styles, and the complexity of the issues make a quick deal unlikely.

What does the realignment of the big NCAA conferences tell us about the future of college sports? NPR's Daniel Estrin talks to Daniel Libit, a reporter at Sportico.

Winston-Salem/Forsyth County was one of only three North Carolina districts with schools named Magnet Schools of Excellence, the highest honor.

Vice President JD Vance is in Pakistan for peace talks with Iran.

Israel continued strikes on Lebanon Friday as Iran insisted on a cease-fire there in order for formal negotiations with the U.S. to begin.