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After a decades long man hunt the defacto head of Mexico's Sinaloa drug cartel is arrested just outside El Paso. What more do we know about his capture and what impact, if any, will this have on the fentanyl crisis here.

The Bureau of Prisons is going forward with plans to move transgender inmates out of prisons that align with their gender identity and into facilities that align with their assigned sex at birth.

We celebrate the NBC mockumentary by listening back to archival interviews with Carell, Gervais, Jenna Fischer, John Krasinski, Rainn Wilson, Mindy Kaling and executive producer Greg Daniels.

President-elect Trump plans to nominate hedge fund manager Scott Bessent to be Treasury Secretary. He's been on of Trump's biggest cheerleaders in the financial world.

President Trump's executive order that the federal government recognizes only two sexes, male and female, is disrupting the lives of some trans, nonbinary and intersex people applying for passports.

A new study shows that giving mice the human version of a gene changes their squeak, suggesting some of the genetic underpinnings of language.

The Maine Principals' Association said it would continue to allow trans girls to compete in school sports, saying President Trump's recent executive order is in conflict with state law.

A number of federal agencies, from HHS to the USDA, have laid off employees only to rescind those terminations days later. An expert says it "suggests something about mismanagement of government."

President-elect Trump wants Kash Patel to lead the FBI. He is also making tariff threats that could be mostly bluster. It's impossible to tell.

If All Else Fails is a podcast from North Country Public Radio that explores how far-right extremism is gaining traction in upstate New York among law enforcement.