A Frontier Airlines plane bound for Los Angeles on Friday night struck and killed a pedestrian who was crossing the runway, according to Denver International Airport.
The collision happened around 11:19 p.m. local time as the aircraft prepared to take off to California.
"Smoke was reported in the cabin and the pilots aborted takeoff," Frontier said in a statement.
"Passengers were then safely evacuated via slides as a matter of precaution."
The airline said it was "deeply saddened" by the event.
ABC News reported that the person struck was "at least partially consumed" by one of the craft's engines, leading to a brief fire.
Denver International said the person was not believed to have been an onsite worker.
"DEN can confirm the pedestrian jumped the perimeter fence and was hit just two minutes later while crossing the runway," the airport said in a statement.
"The pedestrian is deceased, and is not believed to be an employee of the airport nor have they been identified. The airport has examined the fenceline and found it to be intact."
The airport said 12 people reported minor injuries, with five of those individuals taken to local hospitals for treatment.
The Airbus A321 was at the time carrying 224 passengers and seven crew members. Airport authorities said the majority of those passengers have since taken off for Los Angeles on a new Frontier flight.
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